Analysis of Bioassays (optional module)
UNISTAT's optional Analysis of Bioassays module is probably the most comprehensive implementation of the subject in any statistical package. It is based on Finney, D. J. (1978), Biostatistical Method in Biological Assay, and furthermore, it is also a complete implementation of the specification given in European Pharmacopoeia, Statistical Analysis of Results of Biological Assays and Tests.
Potency calculations can be performed employing parallel line, slope ratio and quantal response methods, complete with fiducial confidence intervals, validity tests and graphical representations.
The Analysis of Bioassays module is validated against many examples provided in above publications and it is ready for use in a regulated environment.
You can view sample output from bioassay analysis procedures by clicking on Features / Procedures.
For full information see UNISTAT's online help Chapter 10. Analysis of Bioassays.
Other types of bioassays and effective dose (or ED50) applications can be analysed using UNISTAT’s Nonlinear Regression (see section 7.2.4. Nonlinear Regression) and Logit / Probit / Weibull (see 7.2.5. Logit / Probit / Weibull) procedures.